OPRK1 Antikörper (AA 321-370)

Produktnummer ABIN1535849

Der Kaninchen Polyklonal anti-OPRK1 Antikörper (ABIN1535849) detektiert spezifisch OPRK1 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus und Affe.

Kurzübersicht für OPRK1 Antikörper (AA 321-370) (ABIN1535849)

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-OPRK1 Antikörper

Bindungsspezifität: AA 321-370

Verwendungszweck: KOR-1 Antibody

Spezifität: KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human OPRK1. AA range:321-370

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu OPRK1

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Andere Bezeichnung: OPRK1

Hintergrund:

Synonyms: OPRK1, OPRK, Kappa-type opioid receptor, K-OR-1, KOR-1

Background: This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jan 2016],

Gene Name: OPRK1

Protein Name: Kappa-type opioid receptor

Molekulargewicht: 42 kDa

Gen-ID: 4986

OMIM: 165196

UniProt: P41145