OPN4 Antikörper (AA 429-478)

Produktnummer ABIN1535846

Der Kaninchen Polyklonal anti-OPN4 Antikörper (ABIN1535846) detektiert spezifisch OPN4 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für OPN4 Antikörper (AA 429-478) (ABIN1535846)

Target: OPN4 (Opsin 4 (OPN4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPN4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-OPN4 Antikörper

Bindungsspezifität: AA 429-478

Verwendungszweck: Melanopsin Antibody

Spezifität: Melanopsin Polyclonal Antibody detects endogenous levels of Melanopsin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human OPN4. AA range:429-478

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu OPN4

Target: OPN4 (Opsin 4 (OPN4))

Andere Bezeichnung: OPN4

Hintergrund:

Synonyms: OPN4, MOP, Melanopsin, Opsin-4

Background: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily.This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by Ref

Gene Name: OPN4

Protein Name: Melanopsin

Molekulargewicht: 52 kDa

Gen-ID: 94233

OMIM: 606665

UniProt: Q9UHM6