GRM7 Antikörper (AA 351-400)

Produktnummer ABIN1535757

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GRM7 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für GRM7 Antikörper (AA 351-400) (ABIN1535757)

Target: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRM7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-GRM7 Antikörper

Bindungsspezifität: AA 351-400

Verwendungszweck: mGluR7 Antibody

Spezifität: MGluR7 Polyclonal Antibody detects endogenous levels of mGluR7 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GRM7. AA range:351-400

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GRM7

Target: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Andere Bezeichnung: GRM7

Hintergrund:

Synonyms: GRM7, GPRC1G, MGLUR7, Metabotropic glutamate receptor 7, mGluR7

Background: glutamate metabotropic receptor 7(GRM7) Homo sapiens L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found

Gene Name: GRM7

Protein Name: Metabotropic glutamate receptor 7

Molekulargewicht: 102 kDa

Gen-ID: 2917

OMIM: 604101

UniProt: Q14831

Pathways: Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour