GABBR1 Antikörper (AA 891-940)

Produktnummer ABIN1535688

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GABBR1 in WB, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus und Meerschweinchen.Es wurde in 1 Publikation zitiert.

Kurzübersicht für GABBR1 Antikörper (AA 891-940) (ABIN1535688)

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reaktivität: Human, Ratte, Maus, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-GABBR1 Antikörper

Bindungsspezifität: AA 891-940

Verwendungszweck: GABAB R1 Antibody

Spezifität: GABAB R1 Polyclonal Antibody detects endogenous levels of GABAB R1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GABBR1. AA range:891-940

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Referenzen für anti-GABBR1 Antikörper (ABIN1535688)

Ullrich, Göhmann, Zemella, Kubick: "Oligomerization of the heteromeric γ-aminobutyric acid receptor GABAB in a eukaryotic cell-free system." in: Scientific reports, Vol. 12, Issue 1, pp. 20742, (2022) (PubMed).

Details zu GABBR1

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Andere Bezeichnung: GABBR1

Hintergrund:

Synonyms: GABBR1, GPRC3A, Gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1

Background: This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jan 2016],

Gene Name: GABBR1

Protein Name: Gamma-aminobutyric acid type B receptor subunit 1

Molekulargewicht: 108 kDa

Gen-ID: 2550

OMIM: 603540

UniProt: Q9UBS5

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process