BDKRB1 Antikörper (AA 201-250)
Kurzübersicht für BDKRB1 Antikörper (AA 201-250) (ABIN1535653)
Target
Alle BDKRB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 201-250
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Verwendungszweck
- Bradykinin B1 R Antibody
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Spezifität
- Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
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Andere Bezeichnung
- BDKRB1
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Hintergrund
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Synonyms: BDKRB1, BRADYB1, B1 bradykinin receptor, B1R, BK-1 receptor
Background: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions.The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Gene Name: BDKRB1
Protein Name: B1 bradykinin receptor
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Molekulargewicht
- 40 kDa
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Gen-ID
- 623
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OMIM
- 600337
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UniProt
- P46663
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Pathways
- ACE Inhibitor Pathway
Target
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