THO Complex 5 Antikörper (AA 561-610)

Produktnummer ABIN1535451

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch THO Complex 5 in ELISA, WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für THO Complex 5 Antikörper (AA 561-610) (ABIN1535451)

Target: THO Complex 5 (THOC5)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THO Complex 5 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-THO Complex 5 Antikörper

Bindungsspezifität: AA 561-610

Verwendungszweck: FMIP Antibody

Spezifität: FMIP Polyclonal Antibody detects endogenous levels of FMIP protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human THOC5. AA range:561-610

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu THO Complex 5

Target: THO Complex 5 (THOC5)

Andere Bezeichnung: THOC5

Hintergrund:

Synonyms: THOC5, C22orf19, KIAA0983, THO complex subunit 5 homolog, Functional spliceosome-associated protein 79, fSAP79, NF2/meningioma region protein pK1.3, Placental protein 39.2, PP39.2, hTREX90

Background: function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R, which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,

Gene Name: THOC5

Protein Name: THO complex subunit 5 homolog

Molekulargewicht: 78 kDa

Gen-ID: 8563

OMIM: 612733

UniProt: Q13769