SGOL2 Antikörper (AA 681-730)
Kurzübersicht für SGOL2 Antikörper (AA 681-730) (ABIN1535371)
Target
Alle SGOL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 681-730
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Verwendungszweck
- Sgo2 Antibody
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Spezifität
- Sgo2 Polyclonal Antibody detects endogenous levels of Sgo2 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human SGOL2. AA range:681-730
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- SGOL2 (Shugoshin-Like 2 (SGOL2))
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Andere Bezeichnung
- SGOL2
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Hintergrund
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Synonyms: SGOL2, Shugoshin-like 2, Shugoshin-2, Sgo2, Tripin
Background: function:During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the shugoshin family.,subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase.,subunit:Directly interacts with PPP2CA.,
Gene Name: SGOL2
Protein Name: Shugoshin-like 2
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Molekulargewicht
- 144 kDa
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Gen-ID
- 151246
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OMIM
- 612425
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UniProt
- Q562F6
Target
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