RAB11FIP2 Antikörper (AA 340-389)
Kurzübersicht für RAB11FIP2 Antikörper (AA 340-389) (ABIN1535246)
Target
Alle RAB11FIP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 340-389
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Verwendungszweck
- Rab11-FIP2 Antibody
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Spezifität
- Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human RAB11FIP2. AA range:340-389
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))
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Andere Bezeichnung
- RAB11FIP2
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Hintergrund
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Synonyms: RAB11FIP2, KIAA0941, Rab11 family-interacting protein 2, Rab11-FIP2, NRip11
Background: function:A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).,similarity:Contains 1 C2 domain.,subcellular location:Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.,subunit:Homooligomerizes in a Rab11-independent manner. Forms an heterooligomeric complex with RAB11FIP4. Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been activated by GTP binding.,
Gene Name: RAB11FIP2
Protein Name: Rab11 family-interacting protein 2
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Molekulargewicht
- 58 kDa
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Gen-ID
- 22841
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OMIM
- 608599
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UniProt
- Q7L804
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Pathways
- Hormone Transport, Carbohydrate Homeostasis
Target
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