PEX7 Antikörper (AA 204-253)

Produktnummer ABIN1535157

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PEX7 in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PEX7 Antikörper (AA 204-253) (ABIN1535157)

Target: PEX7 (Peroxisomal Biogenesis Factor 7 (PEX7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEX7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-PEX7 Antikörper

Bindungsspezifität: AA 204-253

Verwendungszweck: Peroxin 7 Antibody

Spezifität: Peroxin 7 Polyclonal Antibody detects endogenous levels of Peroxin 7 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PEX7. AA range:204-253

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PEX7

Target: PEX7 (Peroxisomal Biogenesis Factor 7 (PEX7))

Andere Bezeichnung: PEX7

Hintergrund:

Synonyms: PEX7, PTS2R, Peroxisomal targeting signal 2 receptor, PTS2 receptor, Peroxin-7

Background: This gene encodes the cytosolic receptor for the set of peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2). Defects in this gene cause peroxisome biogenesis disorders (PBDs), which are characterized by multiple defects in peroxisome function. There are at least 14 complementation groups for PBDs, with more than one phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene have been associated with PBD complementation group 11 (PBD-CG11) disorders, rhizomelic chondrodysplasia punctata type 1 (RCDP1), and Refsum disease (RD). [provided by RefSeq, Oct 2008],

Gene Name: PEX7

Protein Name: Peroxisomal targeting signal 2 receptor

Molekulargewicht: 35 kDa

Gen-ID: 5191

OMIM: 601757

UniProt: O00628

Pathways: Monocarboxylic Acid Catabolic Process