NCOA7 Antikörper (AA 422-471)

Produktnummer ABIN1535121

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NCOA7 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für NCOA7 Antikörper (AA 422-471) (ABIN1535121)

Target: NCOA7 (Nuclear Receptor Coactivator 7 (NCOA7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOA7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-NCOA7 Antikörper

Bindungsspezifität: AA 422-471

Verwendungszweck: NCoA-7 Antibody

Spezifität: NCoA-7 Polyclonal Antibody detects endogenous levels of NCoA-7 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NCOA7. AA range:422-471

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NCOA7

Target: NCOA7 (Nuclear Receptor Coactivator 7 (NCOA7))

Andere Bezeichnung: NCOA7

Hintergrund:

Synonyms: NCOA7, ERAP140, ESNA1, Nbla00052, Nbla10993, Nuclear receptor coactivator 7, 140 kDa estrogen receptor-associated protein, Estrogen nuclear receptor coactivator 1

Background: function:Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.,similarity:Belongs to the OXR1 family.,similarity:Contains 1 LysM repeat.,similarity:Contains 1 TLD domain.,subunit:Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT.,tissue specificity:Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.,

Gene Name: NCOA7

Protein Name: Nuclear receptor coactivator 7

Molekulargewicht: 106 kDa

Gen-ID: 135112

OMIM: 609752

UniProt: Q8NI08

Pathways: Nuclear Hormone Receptor Binding