NREP Antikörper (AA 13-62)

Produktnummer ABIN1535102

Der Kaninchen Polyklonal anti-NREP Antikörper (ABIN1535102) detektiert spezifisch NREP in ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für NREP Antikörper (AA 13-62) (ABIN1535102)

Target: NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NREP Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-NREP Antikörper

Bindungsspezifität: AA 13-62

Verwendungszweck: P311 Antibody

Spezifität: P311 Polyclonal Antibody detects endogenous levels of P311 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human C5orf13. AA range:13-62

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NREP

Target: NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))

Andere Bezeichnung: C5orf13

Hintergrund:

Synonyms: NREP, C5orf13, P311, Neuronal regeneration-related protein, Neuronal protein 3.1, Protein p311

Background: P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability, the gene encoding P311 maps to human chromosome 5q22.

Gene Name: NREP

Protein Name: Neuronal regeneration-related protein

Molekulargewicht: 7 kDa

Gen-ID: 9315

OMIM: 607332

UniProt: Q16612