ME1 Antikörper (AA 468-517)

Produktnummer ABIN1535074

Der Kaninchen Polyklonal anti-ME1 Antikörper wird verwendet zum Nachweis von ME1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für ME1 Antikörper (AA 468-517) (ABIN1535074)

Target: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ME1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ME1 Antikörper

Bindungsspezifität: AA 468-517

Verwendungszweck: Malic enzyme 1 Antibody

Spezifität: Malic enzyme 1 Polyclonal Antibody detects endogenous levels of Malic enzyme 1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ME1. AA range:468-517

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ME1

Target: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Andere Bezeichnung: ME1

Hintergrund:

Synonyms: ME1, NADP-dependent malic enzyme, NADP-ME, Malic enzyme 1

Background: This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008],

Gene Name: ME1

Protein Name: NADP-dependent malic enzyme

Molekulargewicht: 64 kDa

Gen-ID: 4199

OMIM: 154250

UniProt: P48163

Pathways: Regulation of Lipid Metabolism by PPARalpha