CYB5R3 Antikörper (AA 137-186)

Produktnummer ABIN1535070

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CYB5R3 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für CYB5R3 Antikörper (AA 137-186) (ABIN1535070)

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYB5R3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CYB5R3 Antikörper

Bindungsspezifität: AA 137-186

Verwendungszweck: CYB5R3 Antibody

Spezifität: CYB5R3 Polyclonal Antibody detects endogenous levels of CYB5R3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CYB5R3. AA range:137-186

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CYB5R3

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Andere Bezeichnung: CYB5R3

Hintergrund:

Synonyms: CYB5R3, DIA1, NADH-cytochrome b5 reductase 3, B5R, Cytochrome b5 reductase, Diaphorase-1

Background: This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010],

Gene Name: CYB5R3

Protein Name: NADH-cytochrome b5 reductase 3

Molekulargewicht: 34 kDa

Gen-ID: 1727

OMIM: 613213

UniProt: P00387

Pathways: SARS-CoV-2 Protein Interaktom