NAD-ME Antikörper (AA 201-250)

Produktnummer ABIN485674

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NAD-ME in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für NAD-ME Antikörper (AA 201-250) (ABIN485674)

Target: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAD-ME Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-NAD-ME Antikörper

Bindungsspezifität: AA 201-250

Verwendungszweck: ME2 Antibody

Spezifität: ME2 Polyclonal Antibody detects endogenous levels of ME2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ME2. AA range:201-250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NAD-ME

Target: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Andere Bezeichnung: ME2

Hintergrund:

Synonyms: ME2, NAD-dependent malic enzyme, mitochondrial, NAD-ME, Malic enzyme 2

Background: This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009],

Gene Name: ME2

Protein Name: NAD-dependent malic enzyme mitochondrial

Molekulargewicht: 65 kDa

Gen-ID: 4200

OMIM: 154270

UniProt: P23368

Pathways: Production of Molecular Mediator of Immune Response