LAMP3 Antikörper (AA 274-323)
Kurzübersicht für LAMP3 Antikörper (AA 274-323) (ABIN1535014)
Target
Alle LAMP3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 274-323
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Verwendungszweck
- DC-LAMP Antibody
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Spezifität
- DC-LAMP Polyclonal Antibody detects endogenous levels of DC-LAMP protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human LAMP3. AA range:274-323
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Isotyp
- IgG
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Applikationshinweise
- Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))
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Andere Bezeichnung
- LAMP3
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Hintergrund
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Synonyms: LAMP3, DCLAMP, TSC403, Lysosome-associated membrane glycoprotein 3, LAMP-3, Lysosomal-associated membrane protein 3, DC-lysosome-associated membrane glycoprotein, DC LAMP, Protein TSC403, CD antigen CD208
Background: MET proto-oncogene, receptor tyrosine kinase(MET) Homo sapiens This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016],
Gene Name: LAMP3
Protein Name: Lysosome-associated membrane glycoprotein 3
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Molekulargewicht
- 44 kDa
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OMIM
- 605883
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UniProt
- Q9UQV4
Target
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