IQCB1 Antikörper (AA 431-480)

Produktnummer ABIN1534993

Der Kaninchen Polyklonal anti-IQCB1 Antikörper wird verwendet zum Nachweis von IQCB1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für IQCB1 Antikörper (AA 431-480) (ABIN1534993)

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IQCB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-IQCB1 Antikörper

Bindungsspezifität: AA 431-480

Verwendungszweck: Nephrocystin-5 Antibody

Spezifität: Nephrocystin-5 Polyclonal Antibody detects endogenous levels of Nephrocystin-5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IQCB1. AA range:431-480

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Andere Bezeichnung: IQCB1

Hintergrund:

Synonyms: IQCB1, KIAA0036, NPHP5, OK/SW-cl.85, IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ

Background: This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Jan 2016],

Gene Name: IQCB1

Protein Name: IQ calmodulin-binding motif-containing protein 1

Molekulargewicht: 68 kDa

Gen-ID: 9657

OMIM: 609237

UniProt: Q15051