GABRD Antikörper (AA 141-190)
Kurzübersicht für GABRD Antikörper (AA 141-190) (ABIN485541)
Target
Alle GABRD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 141-190
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Verwendungszweck
- GABAA Rδ Antibody
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Spezifität
- GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human GABRD. AA range:141-190
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- GABRD (GABA A Receptor delta (GABRD))
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Andere Bezeichnung
- GABRD
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Hintergrund
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Synonyms: GABRD, Gamma-aminobutyric acid receptor subunit delta, GABA(A) receptor subunit delta
Background: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho.This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
Gene Name: GABRD
Protein Name: Gamma-aminobutyric acid receptor subunit delta
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Molekulargewicht
- 50 kDa
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Gen-ID
- 2563
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OMIM
- 137163
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UniProt
- O14764
Target
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