GABRD Antikörper (AA 141-190)

Produktnummer ABIN1534922

Der Kaninchen Polyklonal anti-GABRD Antikörper (ABIN1534922) detektiert spezifisch GABRD in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für GABRD Antikörper (AA 141-190) (ABIN1534922)

Target: GABRD (GABA A Receptor delta (GABRD))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-GABRD Antikörper

Bindungsspezifität: AA 141-190

Verwendungszweck: GABAA Rδ Antibody

Spezifität: GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GABRD. AA range:141-190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GABRD

Target: GABRD (GABA A Receptor delta (GABRD))

Andere Bezeichnung: GABRD

Hintergrund:

Synonyms: GABRD, Gamma-aminobutyric acid receptor subunit delta, GABA(A) receptor subunit delta

Background: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho.This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: GABRD

Protein Name: Gamma-aminobutyric acid receptor subunit delta

Molekulargewicht: 50 kDa

Gen-ID: 2563

OMIM: 137163

UniProt: O14764