GPS2 Antikörper (AA 11-60)

Produktnummer ABIN1534916

Der Kaninchen Polyklonal anti-GPS2 Antikörper (ABIN1534916) detektiert spezifisch GPS2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GPS2 Antikörper (AA 11-60) (ABIN1534916)

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GPS2 Antikörper

Bindungsspezifität: AA 11-60

Verwendungszweck: GPS2 Antibody

Spezifität: GPS2 Polyclonal Antibody detects endogenous levels of GPS2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GPS2. AA range:11-60

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GPS2

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Andere Bezeichnung: GPS2

Hintergrund:

Synonyms: GPS2, G protein pathway suppressor 2, GPS-2

Background: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008],

Gene Name: GPS2

Protein Name: G protein pathway suppressor 2

Molekulargewicht: 36 kDa

Gen-ID: 2874

OMIM: 601935

UniProt: Q13227