Desmoglein 2 Antikörper (AA 401-450)
Kurzübersicht für Desmoglein 2 Antikörper (AA 401-450) (ABIN1534829)
Target
Alle Desmoglein 2 (DSG2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 401-450
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Verwendungszweck
- Dsg2 Antibody
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Spezifität
- Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human DSG2. AA range:401-450
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- Desmoglein 2 (DSG2)
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Andere Bezeichnung
- DSG2
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Hintergrund
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Synonyms: DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC
Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016],
Gene Name: DSG2
Protein Name: Desmoglein-2
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Molekulargewicht
- 122 kDa
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Gen-ID
- 1829
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OMIM
- 125671
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UniProt
- Q14126
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Pathways
- Cell-Cell Junction Organization
Target
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