Claudin 19 Antikörper (AA 81-130)

Produktnummer ABIN1534781

Der Kaninchen Polyklonal anti-Claudin 19 Antikörper (ABIN1534781) detektiert spezifisch Claudin 19 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.

Kurzübersicht für Claudin 19 Antikörper (AA 81-130) (ABIN1534781)

Target: Claudin 19 (CLDN19)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Claudin 19 Antikörper

Bindungsspezifität: AA 81-130

Verwendungszweck: Claudin-19 Antibody

Spezifität: Claudin-19 Polyclonal Antibody detects endogenous levels of Claudin-19 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CLDN19. AA range:81-130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Claudin 19

Target: Claudin 19 (CLDN19)

Andere Bezeichnung: CLDN19

Hintergrund:

Synonyms: CLDN19, Claudin-19

Background: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010],

Gene Name: CLDN19

Protein Name: Claudin-19

Molekulargewicht: 23 kDa

Gen-ID: 149461

OMIM: 610036

UniProt: Q8N6F1

Pathways: Cell-Cell Junction Organization, Hepatitis C