CLCN4 Antikörper (AA 221-270)

Produktnummer ABIN1534766

Der Kaninchen Polyklonal anti-CLCN4 Antikörper (ABIN1534766) detektiert spezifisch CLCN4 in WB, IF und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für CLCN4 Antikörper (AA 221-270) (ABIN1534766)

Target: CLCN4 (Chloride Channel 4 (CLCN4))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLCN4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA

Produktdetails anti-CLCN4 Antikörper

Bindungsspezifität: AA 221-270

Verwendungszweck: CLC-4 Antibody

Spezifität: CLC-4 Polyclonal Antibody detects endogenous levels of CLC-4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CLCN4. AA range:221-270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CLCN4

Target: CLCN4 (Chloride Channel 4 (CLCN4))

Andere Bezeichnung: CLCN4

Hintergrund:

Synonyms: CLCN4, H(+)/Cl(-) exchange transporter 4, Chloride channel protein 4, ClC-4, Chloride transporter ClC-4

Background: chloride voltage-gated channel 4(CLCN4) Homo sapiens The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012],

Gene Name: CLCN4

Protein Name: H(+)/Cl(-) exchange transporter 4

Molekulargewicht: 84 kDa

Gen-ID: 1183

OMIM: 302910

UniProt: P51793