BAIAP2L1 Antikörper (AA 111-160)

Produktnummer ABIN1534702

Der Kaninchen Polyklonal anti-BAIAP2L1 Antikörper wird verwendet zum Nachweis von BAIAP2L1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für BAIAP2L1 Antikörper (AA 111-160) (ABIN1534702)

Target: BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAIAP2L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-BAIAP2L1 Antikörper

Bindungsspezifität: AA 111-160

Verwendungszweck: IRTKS Antibody

Spezifität: IRTKS Polyclonal Antibody detects endogenous levels of IRTKS protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human BAIAP2L1. AA range:111-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu BAIAP2L1

Target: BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Andere Bezeichnung: BAIAP2L1

Hintergrund:

Synonyms: BAIAP2L1, IRTKS, Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, BAI1-associated protein 2-like protein 1, Insulin receptor tyrosine kinase substrate

Background: This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain.The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal fo

Gene Name: BAIAP2L1

Protein Name: Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1

Molekulargewicht: 56 kDa

Gen-ID: 55971

OMIM: 611877

UniProt: Q9UHR4

Pathways: Regulation of Actin Filament Polymerization