ABHD12 Antikörper (AA 231-280)

Produktnummer ABIN1534580

Der Kaninchen Polyklonal anti-ABHD12 Antikörper (ABIN1534580) detektiert spezifisch ABHD12 in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ABHD12 Antikörper (AA 231-280) (ABIN1534580)

Target: ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABHD12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ABHD12 Antikörper

Bindungsspezifität: AA 231-280

Verwendungszweck: ABHD12 Antibody

Spezifität: ABHD12 Polyclonal Antibody detects endogenous levels of ABHD12 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ABHD12. AA range:231-280

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ABHD12

Target: ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))

Andere Bezeichnung: ABHD12

Hintergrund:

Synonyms: ABHD12, C20orf22, Monoacylglycerol lipase ABHD12, 2-arachidonoylglycerol hydrolase, Abhydrolase domain-containing protein 12

Background: This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011],

Gene Name: ABHD12

Protein Name: Monoacylglycerol lipase ABHD12

Molekulargewicht: 45 kDa

Gen-ID: 26090

UniProt: Q8N2K0