MRPL22 Antikörper (AA 91-140)

Produktnummer ABIN1534525

Der Kaninchen Polyklonal anti-MRPL22 Antikörper wird verwendet zum Nachweis von MRPL22 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für MRPL22 Antikörper (AA 91-140) (ABIN1534525)

Target: MRPL22 (Mitochondrial Ribosomal Protein L22 (MRPL22))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MRPL22 Antikörper

Bindungsspezifität: AA 91-140

Verwendungszweck: MRP-L22 Antibody

Spezifität: MRP-L22 Polyclonal Antibody detects endogenous levels of MRP-L22 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPL22. AA range:91-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MRPL22

Target: MRPL22 (Mitochondrial Ribosomal Protein L22 (MRPL22))

Andere Bezeichnung: MRPL22

Hintergrund:

Synonyms: MRPL22, MRPL25, RPML25, HSPC158, 39S ribosomal protein L22, mitochondrial, L22mt, MRP-L22, 39S ribosomal protein L25, mitochondrial, L25mt, MRP-L25

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provide

Gene Name: MRPL22

Protein Name: 39S ribosomal protein L22 mitochondrial

Molekulargewicht: 23 kDa

Gen-ID: 29093

OMIM: 611835

UniProt: Q9NWU5