LAMA3 Antikörper (AA 2571-2620)

Produktnummer ABIN1534453

Der Kaninchen Polyklonal anti-LAMA3 Antikörper wird verwendet zum Nachweis von LAMA3 in Proben von Human, Maus und Ratte. Er wurde validiert für IHC, ELISA, IF und WB.

Kurzübersicht für LAMA3 Antikörper (AA 2571-2620) (ABIN1534453)

Target: LAMA3 (Laminin, alpha 3 (LAMA3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAMA3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Western Blotting (WB)

Produktdetails anti-LAMA3 Antikörper

Bindungsspezifität: AA 2571-2620

Verwendungszweck: Laminin α-3 Antibody

Spezifität: Laminin α-3 Polyclonal Antibody detects endogenous levels of Laminin α-3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human LAMA3. AA range:2571-2620

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu LAMA3

Target: LAMA3 (Laminin, alpha 3 (LAMA3))

Andere Bezeichnung: LAMA3

Hintergrund:

Synonyms: LAMA3, LAMNA, Laminin subunit alpha-3, Epiligrin 170 kDa subunit, E170, Epiligrin subunit alpha, Kalinin subunit alpha, Laminin-5 subunit alpha, Laminin-6 subunit alpha, Laminin-7 subunit alpha, Nicein subunit alpha

Background: The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction.This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014],

Gene Name: LAMA3

Protein Name: Laminin subunit alpha-3

Molekulargewicht: 189 kDa

Gen-ID: 3909

OMIM: 226700

UniProt: Q16787