Cadherin 7 Antikörper (AA 651-700)
Kurzübersicht für Cadherin 7 Antikörper (AA 651-700) (ABIN1534297)
Target
Alle Cadherin 7 (CDH7) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 651-700
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Verwendungszweck
- Cadherin-7 Antibody
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Spezifität
- Cadherin-7 Polyclonal Antibody detects endogenous levels of Cadherin-7 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human CDH7. AA range:651-700
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- Cadherin 7 (CDH7)
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Andere Bezeichnung
- CDH7
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Hintergrund
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Synonyms: CDH7, CDH7L1, Cadherin-7
Background: This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in this gene may be associated with bipolar disease in human patients. This gene is present in a gene cluster on chromosome 18. [provided by RefSeq, May 2016],
Gene Name: CDH7
Protein Name: Cadherin-7
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Molekulargewicht
- 87 kDa
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Gen-ID
- 1005
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OMIM
- 605806
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UniProt
- Q9ULB5
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Pathways
- Cell-Cell Junction Organization
Target
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