Cadherin 20 Antikörper (AA 111-160)
Kurzübersicht für Cadherin 20 Antikörper (AA 111-160) (ABIN1534289)
Target
Alle Cadherin 20 (CDH20) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 111-160
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Verwendungszweck
- Cadherin-20 Antibody
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Spezifität
- Cadherin-20 Polyclonal Antibody detects endogenous levels of Cadherin-20 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human CDH20. AA range:111-160
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- Cadherin 20 (CDH20)
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Andere Bezeichnung
- CDH20
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Hintergrund
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Synonyms: CDH20, CDH7L3, Cadherin-20
Background: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008],
Gene Name: CDH20
Protein Name: Cadherin-20
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Molekulargewicht
- 89 kDa
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Gen-ID
- 28316
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OMIM
- 605807
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UniProt
- Q9HBT6
Target
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