OB Cadherin Antikörper (AA 421-470)

Produktnummer ABIN1534282

Der Kaninchen Polyklonal anti-OB Cadherin Antikörper wird verwendet zum Nachweis von OB Cadherin in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für OB Cadherin Antikörper (AA 421-470) (ABIN1534282)

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OB Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-OB Cadherin Antikörper

Bindungsspezifität: AA 421-470

Verwendungszweck: OB-cadherin Antibody

Spezifität: OB-cadherin Polyclonal Antibody detects endogenous levels of OB-cadherin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CDH11. AA range:421-470

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu OB Cadherin

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Andere Bezeichnung: CDH11

Hintergrund:

Synonyms: CDH11, Cadherin-11, OSF-4, Osteoblast cadherin, OB-cadherin

Background: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008],

Gene Name: CDH11

Protein Name: Cadherin-11

Molekulargewicht: 87 kDa

Gen-ID: 1009

OMIM: 600023

UniProt: P55287