Apoptosis Inhibitor 5 Antikörper (AA 421-470)

Produktnummer ABIN1534266

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Apoptosis Inhibitor 5 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Apoptosis Inhibitor 5 Antikörper (AA 421-470) (ABIN1534266)

Target: Apoptosis Inhibitor 5 (API5)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Apoptosis Inhibitor 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Apoptosis Inhibitor 5 Antikörper

Bindungsspezifität: AA 421-470

Verwendungszweck: API5 Antibody

Spezifität: API5 Polyclonal Antibody detects endogenous levels of API5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human API-5. AA range:421-470

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Apoptosis Inhibitor 5

Target: Apoptosis Inhibitor 5 (API5)

Andere Bezeichnung: API-5

Hintergrund:

Synonyms: API5, MIG8, Apoptosis inhibitor 5, API-5, Antiapoptosis clone 11 protein, AAC-11, Cell migration-inducing gene 8 protein, Fibroblast growth factor 2-interacting factor, FIF, Protein XAGL

Background: This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],

Gene Name: API5

Protein Name: Apoptosis inhibitor 5

Molekulargewicht: 57 kDa

Gen-ID: 8539

OMIM: 609774

UniProt: Q9BZZ5

Pathways: Growth Factor Binding