ADCY5/6 Antikörper (AA 931-980)

Produktnummer ABIN1534255

Der Kaninchen Polyklonal anti-ADCY5/6 Antikörper wird verwendet zum Nachweis von ADCY5/6 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, IF und IHC.

Kurzübersicht für ADCY5/6 Antikörper (AA 931-980) (ABIN1534255)

Target: ADCY5/6 (Adenylate Cyclase 5/6 (ADCY5/6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADCY5/6 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-ADCY5/6 Antikörper

Bindungsspezifität: AA 931-980

Verwendungszweck: A Cyclase V/VI Antibody

Spezifität: A Cyclase V/VI Polyclonal Antibody detects endogenous levels of A Cyclase V/VI protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ADCY5/6. AA range:931-980

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ADCY5/6

Target: ADCY5/6 (Adenylate Cyclase 5/6 (ADCY5/6))

Hintergrund:

Synonyms: ADCY6, KIAA0422, Adenylate cyclase type 6, ATP pyrophosphate-lyase 6, Adenylate cyclase type VI, Adenylyl cyclase 6, Ca(2+)-inhibitable adenylyl cyclase, ADCY5, Adenylate cyclase type 5, ATP pyrophosphate-lyase 5, Adenylate cyclase type V,

Background: This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015],

Gene Name: ADCY5/ADCY6

Protein Name: Adenylate cyclase type 5/6

Molekulargewicht: 130 kDa

Gen-ID: 112, 111

OMIM: 600294

UniProt: O43306