CREBZF Antikörper (AA 221-270)

Produktnummer ABIN1534147

Der Kaninchen Polyklonal anti-CREBZF Antikörper wird verwendet zum Nachweis von CREBZF in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IF und IHC.

Kurzübersicht für CREBZF Antikörper (AA 221-270) (ABIN1534147)

Target: CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CREBZF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-CREBZF Antikörper

Bindungsspezifität: AA 221-270

Verwendungszweck: Zhangfei Antibody

Spezifität: Zhangfei Polyclonal Antibody detects endogenous levels of Zhangfei protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CREBZF. AA range:221-270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CREBZF

Target: CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

Andere Bezeichnung: CREBZF

Hintergrund:

Synonyms: CREBZF, ZF, CREB/ATF bZIP transcription factor, Host cell factor-binding transcription factor Zhangfei, HCF-binding transcription factor Zhangfei

Background: function:Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.,miscellaneous:Named Zhangfei after a legendary Chinese warrior who was contemporary with Luman in around 220 AD.,similarity:Belongs to the bZIP family. ATF subfamily.,similarity:Contains 1 bZIP domain.,subcellular location:Colocalizes at punctate nuclear structures with CREB3 and HCFC1.,subunit:Interacts with HCFC1, causing suppression of CREB3 transcriptional activity.,tissue specificity:In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lungs. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.,

Gene Name: CREBZF

Protein Name: CREB/ATF bZIP transcription factor

Molekulargewicht: 28 kDa

Gen-ID: 58487

OMIM: 606444

UniProt: Q9NS37