DLC1 Antikörper (AA 61-110)

Produktnummer ABIN1534080

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DLC1 in IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für DLC1 Antikörper (AA 61-110) (ABIN1534080)

Target: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-DLC1 Antikörper

Bindungsspezifität: AA 61-110

Verwendungszweck: DLC-1 Antibody

Spezifität: DLC-1 Polyclonal Antibody detects endogenous levels of DLC-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RHG07. AA range:61-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu DLC1

Target: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Hintergrund:

Synonyms: DLC1, ARHGAP7, KIAA1723, STARD12, Rho GTPase-activating protein 7, Deleted in liver cancer 1 protein, DLC-1, HP protein, Rho-type GTPase-activating protein 7, START domain-containing protein 12, StARD12, StAR-related lipid transfer protein

Background: This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010],

Gene Name: DLC1

Protein Name: Rho GTPase-activating protein 7

Molekulargewicht: 122 kDa

Gen-ID: 10395

OMIM: 604258

UniProt: Q96QB1

Pathways: Tube Formation, Positive Regulation of Endopeptidase Activity