PHKB Antikörper (AA 661-710)

Produktnummer ABIN1534055

Der Kaninchen Polyklonal anti-PHKB Antikörper (ABIN1534055) detektiert spezifisch PHKB in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für PHKB Antikörper (AA 661-710) (ABIN1534055)

Target: PHKB (Phosphorylase Kinase, beta (PHKB))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHKB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PHKB Antikörper

Bindungsspezifität: AA 661-710

Verwendungszweck: PHKB Antibody

Spezifität: PHKB Polyclonal Antibody detects endogenous levels of PHKB protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human KPBB. AA range:661-710

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PHKB

Target: PHKB (Phosphorylase Kinase, beta (PHKB))

Hintergrund:

Synonyms: PHKB, Phosphorylase b kinase regulatory subunit beta, Phosphorylase kinase subunit beta

Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency

Gene Name: PHKB

Protein Name: Phosphorylase b kinase regulatory subunit beta

Molekulargewicht: 124 kDa

Gen-ID: 5257

OMIM: 172490

UniProt: Q93100

Pathways: Cellular Glucan Metabolic Process