Histone H2B Antikörper (AA 1-50)

Produktnummer ABIN1534054

Der Kaninchen Polyklonal anti-Histone H2B Antikörper wird verwendet zum Nachweis von Histone H2B in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IF, ICC und IHC (p).

Kurzübersicht für Histone H2B Antikörper (AA 1-50) (ABIN1534054)

Target: Histone H2B

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone H2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Histone H2B Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: Histone H2B Antibody

Spezifität: Histone H2B Polyclonal Antibody detects endogenous levels of Histone H2B protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Histone H2B. AA range:1-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Histone H2B

Target: Histone H2B

Hintergrund:

Synonyms: HIST1H2BH, H2BFJ, Histone H2B type 1-H, Histone H2B.j, H2B/j

Background: folate hydrolase 1(FOLH1) Homo sapiens This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alter

Gene Name: HIST1H2BH

Protein Name: Histone H2B type 1-H

Molekulargewicht: 13 kDa

OMIM: 602806

UniProt: Q93079