DCLK2 Antikörper (AA 1-50)

Produktnummer ABIN1534000

Der Kaninchen Polyklonal anti-DCLK2 Antikörper wird verwendet zum Nachweis von DCLK2 in Proben von Human und Maus. Er wurde validiert für WB, ELISA und IF.

Kurzübersicht für DCLK2 Antikörper (AA 1-50) (ABIN1534000)

Target: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCLK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-DCLK2 Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: DCAMKL2 Antibody

Spezifität: DCAMKL2 Polyclonal Antibody detects endogenous levels of DCAMKL2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human DCLK2. AA range:1-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu DCLK2

Target: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Andere Bezeichnung: DCLK2

Hintergrund:

Synonyms: DCLK2, DCAMKL2, DCDC3B, DCK2, Serine/threonine-protein kinase DCLK2, CaMK-like CREB regulatory kinase 2, CL2, CLICK-II, CLICK2, Doublecortin domain-containing protein 3B, Doublecortin-like and CAM kinase-like 2, Doublecortin-like kinase 2

Background: This gene encodes a member of the protein kinase superfamily and the doublecortin family.The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alterna

Gene Name: DCLK2

Protein Name: Serine/threonine-protein kinase DCLK2

Molekulargewicht: 83 kDa

Gen-ID: 166614

UniProt: Q8N568