AAK1 Antikörper (AA 271-320)

Produktnummer ABIN1533939

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AAK1 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Affe.

Kurzübersicht für AAK1 Antikörper (AA 271-320) (ABIN1533939)

Target: AAK1 (AP2 associated kinase 1 (AAK1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AAK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-AAK1 Antikörper

Bindungsspezifität: AA 271-320

Verwendungszweck: AAK1 Antibody

Spezifität: AAK1 Polyclonal Antibody detects endogenous levels of AAK1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human AAK1. AA range:271-320

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu AAK1

Target: AAK1 (AP2 associated kinase 1 (AAK1))

Andere Bezeichnung: AAK1

Hintergrund:

Synonyms: AAK1, KIAA1048, AP2-associated protein kinase 1, Adaptor-associated kinase 1

Background: Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors.This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: AAK1

Protein Name: AP2-associated protein kinase 1

Molekulargewicht: 93 kDa

Gen-ID: 22848

UniProt: Q2M2I8