ZFHX3 Antikörper (AA 761-810)

Produktnummer ABIN1533928

Der Kaninchen Polyklonal anti-ZFHX3 Antikörper wird verwendet zum Nachweis von ZFHX3 in Proben von Human und Maus. Er wurde validiert für ELISA, IHC und IF.

Kurzübersicht für ZFHX3 Antikörper (AA 761-810) (ABIN1533928)

Target: ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFHX3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ZFHX3 Antikörper

Bindungsspezifität: AA 761-810

Verwendungszweck: ATBF1 Antibody

Spezifität: ATBF1 Polyclonal Antibody detects endogenous levels of ATBF1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ZFHX3. AA range:761-810

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ZFHX3

Target: ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))

Andere Bezeichnung: ZFHX3

Hintergrund:

Synonyms: ZFHX3, ATBF1, Zinc finger homeobox protein 3, AT motif-binding factor, AT-binding transcription factor 1, Alpha-fetoprotein enhancer-binding protein, Zinc finger homeodomain protein 3, ZFH-3

Background: This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

Gene Name: ZFHX3

Protein Name: Zinc finger homeobox protein 3

Molekulargewicht: 404 kDa

Gen-ID: 463

OMIM: 104155

UniProt: Q15911

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development