CHD4 Antikörper (AA 571-620)
Kurzübersicht für CHD4 Antikörper (AA 571-620) (ABIN1533894)
Target
Alle CHD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 571-620
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Verwendungszweck
- Mi2-β Antibody
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Spezifität
- Mi2-β Polyclonal Antibody detects endogenous levels of Mi2-β protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human CHD4. AA range:571-620
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))
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Andere Bezeichnung
- CHD4
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Hintergrund
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Synonyms: CHD4, Chromodomain-helicase-DNA-binding protein 4, CHD-4, ATP-dependent helicase CHD4, Mi-2 autoantigen 218 kDa protein, Mi2-beta
Background: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
Gene Name: CHD4
Protein Name: Chromodomain-helicase-DNA-binding protein 4
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Molekulargewicht
- 217 kDa
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Gen-ID
- 1108
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OMIM
- 603277
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UniProt
- Q14839
Target
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