MELK Antikörper (AA 431-480)

Produktnummer ABIN1533892

Der Kaninchen Polyklonal anti-MELK Antikörper wird verwendet zum Nachweis von MELK in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für MELK Antikörper (AA 431-480) (ABIN1533892)

Target: MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MELK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MELK Antikörper

Bindungsspezifität: AA 431-480

Verwendungszweck: MELK Antibody

Spezifität: MELK Polyclonal Antibody detects endogenous levels of MELK protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MELK. AA range:431-480

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MELK

Target: MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))

Andere Bezeichnung: MELK

Hintergrund:

Synonyms: MELK, KIAA0175, Maternal embryonic leucine zipper kinase, hMELK, Protein kinase Eg3, pEg3 kinase, Protein kinase PK38, hPK38, Tyrosine-protein kinase MELK

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.,PTM:Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.,similarity:Contains 1 KA1 (kinase-associated) domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with ZNF622 and PPP1R8.,tissue specificity:Expressed in placenta, kidney, thymus, testis, ovary and intestine.,

Gene Name: MELK

Protein Name: Maternal embryonic leucine zipper kinase

Molekulargewicht: 74 kDa

Gen-ID: 9833

OMIM: 607025

UniProt: Q14680