GCKR Antikörper (AA 211-260)

Produktnummer ABIN1533887

Der Kaninchen Polyklonal anti-GCKR Antikörper (ABIN1533887) detektiert spezifisch GCKR in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für GCKR Antikörper (AA 211-260) (ABIN1533887)

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCKR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GCKR Antikörper

Bindungsspezifität: AA 211-260

Verwendungszweck: GCKR Antibody

Spezifität: GCKR Polyclonal Antibody detects endogenous levels of GCKR protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Glucokinase Regulator. AA range:211-260

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GCKR

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Andere Bezeichnung: Glucokinase Regulator

Hintergrund:

Synonyms: GCKR, Glucokinase regulatory protein, Glucokinase regulator

Background: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008],

Gene Name: GCKR

Protein Name: Glucokinase regulatory protein

Molekulargewicht: 68 kDa

Gen-ID: 2646

OMIM: 600842

UniProt: Q14397

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus