MVK Antikörper (AA 151-200)

Produktnummer ABIN1533828

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MVK in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human und Affe.

Kurzübersicht für MVK Antikörper (AA 151-200) (ABIN1533828)

Target: MVK (Mevalonate Kinase (MVK))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MVK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-MVK Antikörper

Bindungsspezifität: AA 151-200

Verwendungszweck: MVK Antibody

Spezifität: MVK Polyclonal Antibody detects endogenous levels of MVK protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Mevalonate Kinase. AA range:151-200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MVK

Target: MVK (Mevalonate Kinase (MVK))

Andere Bezeichnung: Mevalonate Kinase

Hintergrund:

Synonyms: MVK, Mevalonate kinase, MK

Background: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

Gene Name: MVK

Protein Name: Mevalonate kinase

Molekulargewicht: 42 kDa

Gen-ID: 4598

OMIM: 251170

UniProt: Q03426