ST5 Antikörper (AA 411-460)

Produktnummer ABIN1533807

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ST5 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für ST5 Antikörper (AA 411-460) (ABIN1533807)

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ST5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ST5 Antikörper

Bindungsspezifität: AA 411-460

Verwendungszweck: ST5 Antibody

Spezifität: ST5 Polyclonal Antibody detects endogenous levels of ST5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ST5. AA range:411-460

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Andere Bezeichnung: ST5

Hintergrund:

Synonyms: ST5, DENND2B, HTS1, Suppression of tumorigenicity 5 protein, DENN domain-containing protein 2B, HeLa tumor suppression 1

Background: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice.The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008],

Gene Name: ST5

Protein Name: Suppression of tumorigenicity 5 protein

Molekulargewicht: 126 kDa

Gen-ID: 6764

OMIM: 140750

UniProt: P78524