TMPRSS3 Antikörper (AA 405-454)

Produktnummer ABIN1533796

Der Kaninchen Polyklonal anti-TMPRSS3 Antikörper wird verwendet zum Nachweis von TMPRSS3 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für TMPRSS3 Antikörper (AA 405-454) (ABIN1533796)

Target: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMPRSS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TMPRSS3 Antikörper

Bindungsspezifität: AA 405-454

Verwendungszweck: TMPRSS3 Antibody

Spezifität: TMPRSS3 Polyclonal Antibody detects endogenous levels of TMPRSS3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TMPRSS3. AA range:405-454

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu TMPRSS3

Target: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Andere Bezeichnung: TMPRSS3

Hintergrund:

Synonyms: TMPRSS3, ECHOS1, TADG12, Transmembrane protease serine 3, Serine protease TADG-12, Tumor-associated differentially-expressed gene 12 protein

Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders.This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012],

Gene Name: TMPRSS3

Protein Name: Transmembrane protease serine 3

Molekulargewicht: 49 kDa

Gen-ID: 64699

OMIM: 601072

UniProt: P57727

Pathways: Sensory Perception of Sound