ACTN2/3 Antikörper (AA 31-80)

Produktnummer ABIN1533709

Der Kaninchen Polyklonal anti-ACTN2/3 Antikörper wird verwendet zum Nachweis von ACTN2/3 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, IF und ELISA.

Kurzübersicht für ACTN2/3 Antikörper (AA 31-80) (ABIN1533709)

Target: ACTN2/3 (Actinin, alpha 2/3 (ACTN2/3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACTN2/3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Produktdetails anti-ACTN2/3 Antikörper

Bindungsspezifität: AA 31-80

Verwendungszweck: Actinin-α2/3 Antibody

Spezifität: Actinin-α2/3 Polyclonal Antibody detects endogenous levels of Actinin-α2/3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Actinin alpha-2/3. AA range:31-80

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ACTN2/3

Target: ACTN2/3 (Actinin, alpha 2/3 (ACTN2/3))

Hintergrund:

Synonyms: ACTN2, Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2, F-actin cross-linking protein, ACTN3, Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein

Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],

Gene Name: ACTN2/ACTN3

Protein Name: Alpha-actinin-2/3

Molekulargewicht: 103 kDa

Gen-ID: 88, 89

OMIM: 102573

UniProt: P35609