MYF5 Antikörper (AA 61-110)

Produktnummer ABIN1533615

Der Kaninchen Polyklonal anti-MYF5 Antikörper (ABIN1533615) detektiert spezifisch MYF5 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für MYF5 Antikörper (AA 61-110) (ABIN1533615)

Target: MYF5 (Myogenic Factor 5 (MYF5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MYF5 Antikörper

Bindungsspezifität: AA 61-110

Verwendungszweck: Myf-5 Antibody

Spezifität: Myf-5 Polyclonal Antibody detects endogenous levels of Myf-5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MYF5. AA range:61-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MYF5

Target: MYF5 (Myogenic Factor 5 (MYF5))

Andere Bezeichnung: MYF5

Hintergrund:

Synonyms: MYF5, BHLHC2, Myogenic factor 5, Myf-5, Class C basic helix-loop-helix protein 2, bHLHc2

Background: von Hippel-Lindau tumor suppressor(VHL) Homo sapiens Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome.The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

Gene Name: MYF5

Protein Name: Myogenic factor 5

Molekulargewicht: 28 kDa

OMIM: 159990

UniProt: P13349

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development