FARP2 Antikörper (AA 331-380)

Produktnummer ABIN1533551

Der Kaninchen Polyklonal anti-FARP2 Antikörper (ABIN1533551) detektiert spezifisch FARP2 in ELISA, WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für FARP2 Antikörper (AA 331-380) (ABIN1533551)

Target: FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FARP2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-FARP2 Antikörper

Bindungsspezifität: AA 331-380

Verwendungszweck: FIR Antibody

Spezifität: FIR Polyclonal Antibody detects endogenous levels of FIR protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FIR. AA range:331-380

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu FARP2

Target: FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))

Andere Bezeichnung: FIR

Hintergrund:

Synonyms: FARP2, KIAA0793, PLEKHC3, FERM, RhoGEF and pleckstrin domain-containing protein 2, FERM domain including RhoGEF, FIR, Pleckstrin homology domain-containing family C member 3, PH domain-containing family C member 3

Background: function:Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 FERM domain.,similarity:Contains 2 PH domains.,subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding.,

Gene Name: FARP2

Protein Name: FERM RhoGEF and pleckstrin domain-containing protein 2

Molekulargewicht: 119 kDa

Gen-ID: 9855

UniProt: O94887