HAT Antikörper (AA 331-380)

Produktnummer ABIN1533428

Der Kaninchen Polyklonal anti-HAT Antikörper (ABIN1533428) detektiert spezifisch HAT in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für HAT Antikörper (AA 331-380) (ABIN1533428)

Target: HAT (Histone Acetyltransferase (HAT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HAT Antikörper

Bindungsspezifität: AA 331-380

Verwendungszweck: HAT1 Antibody

Spezifität: HAT1 Polyclonal Antibody detects endogenous levels of HAT1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HAT. AA range:331-380

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu HAT

Target: HAT (Histone Acetyltransferase (HAT))

Andere Bezeichnung: HAT

Hintergrund:

Synonyms: HAT1, KAT1, Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase 1

Background: The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009],

Gene Name: HAT1

Protein Name: Histone acetyltransferase type B catalytic subunit

Molekulargewicht: 49 kDa

Gen-ID: 8520

OMIM: 603053

UniProt: O14929

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process