Sodium Channel Antikörper (AA 1466-1515)

Produktnummer ABIN1533401

Der Kaninchen Polyklonal anti-Sodium Channel Antikörper (ABIN1533401) detektiert spezifisch Sodium Channel in IHC, ELISA, WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Sodium Channel Antikörper (AA 1466-1515) (ABIN1533401)

Target: Sodium Channel

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sodium Channel Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Sodium Channel Antikörper

Bindungsspezifität: AA 1466-1515

Verwendungszweck: Na+ CP-pan Antibody

Spezifität: Na+ CP-pan Polyclonal Antibody detects endogenous levels of Na+ CP-pan protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Sodium Channel. AA range:1466-1515

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Sodium Channel

Target: Sodium Channel

Hintergrund:

Synonyms: SCN1A; NAC1; SCN1; Sodium channel protein type 1 subunit alpha; Sodium channel protein brain I subunit alpha; Sodium channel protein type I subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.1; SCN2A; NAC2; SCN2A1; SCN2A2; Sodiu

Background: Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits.This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, th

Gene Name: SCN1A/SCN2A/SCN3A/SCN4A/SCN5A/SCN8A/SCN9A/SCN10A/SCN11A

Protein Name: Sodium channel protein type 1 subunit alpha

Molekulargewicht: 227 kDa

Gen-ID: 6323, 6326, 6328

OMIM: 182389

UniProt: P35498