NCK2 Antikörper (AA 331-380)

Produktnummer ABIN1533356

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NCK2 in IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für NCK2 Antikörper (AA 331-380) (ABIN1533356)

Target: NCK2 (NCK Adaptor Protein 2 (NCK2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCK2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-NCK2 Antikörper

Bindungsspezifität: AA 331-380

Verwendungszweck: Nck-2 Antibody

Spezifität: Nck-2 Polyclonal Antibody detects endogenous levels of Nck-2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NCK2. AA range:331-380

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NCK2

Target: NCK2 (NCK Adaptor Protein 2 (NCK2))

Andere Bezeichnung: NCK2

Hintergrund:

Synonyms: NCK2, GRB4, Cytoplasmic protein NCK2, Growth factor receptor-bound protein 4, NCK adaptor protein 2, Nck-2, SH2/SH3 adaptor protein NCK-beta

Background: This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Gene Name: NCK2

Protein Name: Cytoplasmic protein NCK2

Molekulargewicht: 42 kDa

Gen-ID: 8440

OMIM: 604930

UniProt: O43639

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization